Echelon 是脂質(zhì)研究和脂質(zhì)與蛋白質(zhì)相互作用研究領(lǐng)域的*。脂質(zhì)蛋白相互作用是眾多的細(xì)胞信號(hào)通路中高級(jí)調(diào)控*的。異常的細(xì)胞信號(hào)通路將會(huì)導(dǎo)致許多疾病，例如癌癥，炎癥，糖尿病和心血管疾病。數(shù)年來(lái)，Echelon一直是脂質(zhì)研究信息，脂質(zhì)信號(hào)分析和試劑技術(shù)的供應(yīng)商。
 高品質(zhì)的合成磷脂，磷酸肌醇，鞘脂及其衍生物
 脂質(zhì)與蛋白質(zhì)相互作用工具
 脂質(zhì)含量檢測(cè)試劑盒
 脂質(zhì)相關(guān)生物酶活性檢測(cè)，抑制劑篩選試劑盒
 優(yōu)質(zhì)的樣品檢測(cè)服務(wù)及客戶(hù)服務(wù)
 脂質(zhì)蛋白相互作用工具

 Lipid Strips/Arrays  
產(chǎn)品PIP StripsTM, PIP ArraysTM:
簡(jiǎn)單蛋白質(zhì)疊加實(shí)驗(yàn)可以快速識(shí)別和定量脂質(zhì)、蛋白質(zhì)相互作用。
包括所有八種磷酸肌醇。
Echelon,P-6001脂類(lèi)試紙

PIP Strips are 2 x 6 cm hydrophobic membranes that have been spotted with 100 pmol of all eight phosphoinositides and seven other biological important lipids. They are used to determine how your protein of interest interacts with one or more of these lipids in a simple protein-lipid overlay assay. Bound protein is then detected by an antibody against the protein or affinity tag.

PIP膜試紙條是2 x 6 cm的疏水膜，包含8種磷脂和7種其他重要的生物脂類(lèi)，被用來(lái)確定你感興趣的蛋白質(zhì)如何與一個(gè)或多個(gè)這些脂質(zhì)在一個(gè)簡(jiǎn)單的蛋白質(zhì)脂質(zhì)重疊分析。包含以下:
1.Lysophosphatidic acid (LPA) 溶血磷脂酸（LPA）

2.Lysophosphocholine (LPC) 溶血磷脂
3.Phosphatidylinositol (PtdIns)  磷脂酰肌醇
4.Phosphatidylinositol (3)-phosphate (PtdIns(3)P) 磷脂酰肌醇（3）-磷酸
5.Phosphatidylinositol (4)-phosphate (PtdIns(4)P) 磷脂酰肌醇（4）-磷酸
6.Phosphatidylinositol (5)-phosphate (PtdIns(5)P) 磷脂酰肌醇（5）-磷酸
7.Phosphatidylethanolamine (PE) 磷脂酰乙   醇    胺
8.Phosphatidylcholine (PC) 磷脂酰膽堿
9.Sphingosine 1-Phosphate (S1P) 1-磷酸鞘氨醇
10.Phosphatidylinositol(3,4)-bisphosphate (PtdIns(3,4)P2 )  磷脂酰肌醇（3,4）-二磷酸
11.Phosphatidylinositol(3,5)-bisphosphate (PtdIns(3,5)P2) 磷脂酰肌醇（3,5）-二磷酸
12.Phosphatidylinositol(4,5)-bisphosphate (PtdIns(4,5)P2) 磷脂酰肌醇（4,5）-二磷酸
13.Phosphatidylinositol(3,4,5)-trisphosphate (PtdIns(3,4,5)P3) 磷脂酰肌醇（3,4,5）-三磷酸
14.Phosphatidic acid (PA) 磷脂酸
15.Phosphatidylserine (PS) 磷脂酰絲氨酸
另外
Each 10-pack of PIP Strips includes a free vial of the PI(4,5)P2 specific binding protein for use as a positive control.---貨號(hào)P-6001-2 規(guī)格10PK，包含G-4501 蛋白；

 發(fā)表文獻(xiàn)：

1)Huang, S., L. Gao, et al. (2006). “Heterodimeric Capping Protein from Arabidopsis Is Regulated by Phosphatidic Acid.” Molecular Biology of the Cell 17(4): 1946-1958.
2)Jin, W., W.-P. Ge, et al. (2006). “Lipid Binding Regulates Synaptic Targeting of PICK1, AMPA Receptor Trafficking, and Synaptic Plasticity.” The Journal of Neuroscience 26(9): 2380-2390.
3)Xi, Q., G. J. T. Pauer, et al. (2005). “Tubby-like Protein 1 (TULP1) Interacts with F-actin in Photoreceptor Cells.” Investigative Ophthalmology & Visual Science 46(12): 4754-4761.
4)Sharma, V. P., V. Desmarais, et al. (2008). “Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells.” J Leukoc Biol 84(2): 440-7.

默瑞生物 

默瑞(上海)生物科技有限公司，作為專(zhuān)業(yè)的生命科學(xué)產(chǎn)品推廣與服務(wù)商，以“創(chuàng)新，專(zhuān)業(yè)，共贏”的理念，不斷強(qiáng)化服務(wù)體系，提升客戶(hù)體驗(yàn)，結(jié)合國(guó)內(nèi)外優(yōu)質(zhì)產(chǎn)品提供高標(biāo)準(zhǔn)完整解決方案，幫助科研客戶(hù)和生物技術(shù)企業(yè)高效創(chuàng)新，加速轉(zhuǎn)化，創(chuàng)造更多優(yōu)質(zhì)產(chǎn)品，提升社會(huì)福祉，實(shí)現(xiàn)多方共贏。

默瑞生物創(chuàng)立以來(lái),已經(jīng)陸續(xù)導(dǎo)入TwistDx,博日

Jackson,izon,Biontex,Immunostep,101Bio,enzymatics,AATBioquest,KAPABIOSYSTEMS,BioDynami,Echelon,ChromoTek,Nanocs,Biotechrabbit,LeeBiosolutions, magtivio等優(yōu)質(zhì)品牌，逐步培育成為專(zhuān)業(yè)用戶(hù)的選擇。